Article

Bayesian inference of transcriptional branching identifies regulators of early germ cell development in humans

2017-07-24

Abstract excerpt

During embryonic development, cells undertake a series of fate decisions to form a complete organism comprised of various cell types, epitomising a branching process. A striking example of branching occurs in humans around the time of implantation, when primordial germ cells (PGCs), precursors of sperm and eggs, and somatic lineages are specified. Due to inaccessibility of human embryos at this stage of developmen...

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Literature Corpus work: 52195ce5-4d2d-599c-92e7-3323ad3b3961
DOI: 10.1101/167684

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