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Article

CTLA-4 and TNFRSF1B genetic variants in clinicopathological aspects and outcome of cutaneous melanoma.

Melanoma research - 1 Aug 2026

Carron Juliana, Ferreira Ana Maria Castro, Carvalho Bruna Fernandes, Lourenço Gustavo Jacob, Lima Carmen Silvia Passos

Abstract excerpt

Cutaneous melanoma is the most aggressive form of skin cancer, influenced by environmental and genetic factors, particularly immune-related genes like cytotoxic T-lymphocyte-associated protein 4 ( CTLA-4 ) and TNFRSF1B . We investigated the association of inherited single nucleotide variants in CTLA-4 (rs11571316, rs62182595, rs11571315, and rs4553808) and TNFRSF1B (rs3397, , , and )...

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Identifiers

PMID: 42186386
DOI: 10.1097/CMR.0000000000001108

Genes

TNFRSF1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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