Article
Melanoma risk loci as determinants of melanoma recurrence and survival.
Journal of translational medicine - 4 Nov 2013
Rendleman Justin, Shang Shulian, Dominianni Christine, Shields Jerry F, Scanlon Patrick, Adaniel Christina, Desrichard Alexis, Ma Michelle, Shapiro Richard, Berman Russell, Pavlick Anna, Polsky David, Shao Yongzhao, Osman Iman, Kirchhoff Tomas
Abstract excerpt
BACKGROUND: Steadily high melanoma mortality rates urge for the availability of novel biomarkers with a more personalized ability to predict melanoma clinical outcomes. Germline risk variants are promising candidates for this purpose; however, their prognostic potential in melanoma has never been systematically tested. METHODS: We examined the effect of 108 melanoma susceptibility single nucleotide polymorphisms...
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