Interleukin-1β Gene (IL1B) rs1143634 (+3954 C>T) Polymorphism and Cutaneous Melanoma Risk: An Observational Case-Control Study in Northeast Italy.

doi:10.3390/genes17070786

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Interleukin-1β Gene (IL1B) rs1143634 (+3954 C>T) Polymorphism and Cutaneous Melanoma Risk: An Observational Case-Control Study in Northeast Italy.

Genes - 9 Jul 2026

Cauci Sabina, Buligan Cinzia, Bazzichetto Luca, Petris Gianluca, Stinco Giuseppe

Abstract excerpt

Background: Immune modulation is central to cutaneous melanoma, and antitumor immune responses may be influenced by host genetic background. This study investigated the association between the interleukin-1β gene (IL1B) exon 5 synonymous single-nucleotide polymorphism rs1143634 (+3954 C>T) and cutaneous melanoma in a Northeast Italian case-control cohort. Methods: The study included 133 Caucasian patients with...

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PMID: 42510826
DOI: 10.3390/genes17070786
PMCID: PMC13409242

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IL1B

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