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Article

Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study.

Cancer medicine - 1 Nov 2016

White Kirsten A M, Luo Li, Thompson Todd A, Torres Salina, Hu Chien-An Andy, Thomas Nancy E, Lilyquist Jenna, Anton-Culver Hoda, Gruber Stephen B, From Lynn, Busam Klaus J, Orlow Irene, Kanetsky Peter A, Marrett Loraine D, Gallagher Richard P, Sacchetto Lidia, Rosso Stefano, Dwyer Terence, Cust Anne E, Begg Colin B, Berwick Marianne

Abstract excerpt

Autophagy has been linked with melanoma risk and survival, but no polymorphisms in autophagy-related (ATG) genes have been investigated in relation to melanoma progression. We examined five single-nucleotide polymorphisms (SNPs) in three ATG genes (ATG5; ATG10; and ATG16L) with known or suspected impact on autophagic flux in an international population-based case-control study of melanoma. DNA from 911 melanoma...

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Source

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Identifiers

PMID: 27748080
DOI: 10.1002/cam4.929
PMCID: PMC5119988

Genes

ATG5
ATG10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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