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Article

Phage-encoded factor stimulates DNA degradation by the Hna anti-phage defense system.

Nature communications - 18 May 2026

Hooper Matthew M, Hoover Benjamin T, Zhang Hongshan, Franco Adam S, Finkelstein Ilya J, Taylor David W

Abstract excerpt

Prokaryotic organisms have evolved unique strategies to acquire immunity against the constant threat of bacteriophage (phage) and mobile genetic elements. Hna is a broadly distributed anti-phage immune system that confers resistance against diverse phage by eliciting an abortive infection response. Using a combination of biochemistry, cryo-electron microscopy, and single-molecule fluorescence imaging, we reveal...

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Share to Adenosine Triphosphate
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42151145
DOI: 10.1038/s41467-026-73157-2
PMCID: PMC13381803

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SSB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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