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The effect of polygenic risk score and childhood adversity experiences on transdiagnostic symptom dimensions at first-episode psychosis: evidence for an affective pathway to psychosis

2024-03-18

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<title>Abstract</title> <p><bold>Background </bold>Childhood adversity is associated with various clinical dimensions in psychosis; however, how genetic vulnerability shapes the adversity associated psychopathological signature is yet to be clarified. <bold>Methods</bold> Using data from the EU-GEI study, in 376 First Episode Psychosis (FEP) cases, we evaluated the interaction between polygenic risk scores for sc...

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Literature Corpus work
a9e208af-e871-5a3e-8e5f-962b52fbc544
DOI
10.21203/rs.3.rs-4032466/v1
Open publication

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The effect of polygenic risk score and childhood adversity experiences on transdiagnostic symptom dimensions at first-episode psychosis: evidence for an affective pathway to psychosisDOI 10.21203/rs.3.rs-4032466/v1
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