Article
Post-partum psychosis and its association with bipolar disorder in the UK: a case-control study using polygenic risk scores.
The lancet. Psychiatry - 1 Dec 2021
Di Florio Arianna, Mei Kay Yang Jessica, Crawford Karen, Bergink Veerle, Leonenko Ganna, Pardiñas Antonio F, Escott-Price Valentina, Gordon-Smith Katherine, Owen Michael J, Craddock Nick, Jones Lisa, O'Donovan Michael, Jones Ian
Abstract excerpt
BACKGROUND: For more than 150 years, controversy over the status of post-partum psychosis has hindered research and caused considerable confusion for clinicians and women, with potentially negative consequences. We aimed to explore the hypothesis that genetic vulnerability differs between women with first-onset post-partum psychosis and those with bipolar disorder more generally. METHODS: In this case-control...
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