Mistranslation suppresses mistranscription in eukaryotes.

Abstract excerpt

Phenotypic mutations include non-heritable sequence changes arising from synthetic errors such as mistranscription or mistranslation. Despite wide potential impact of both error types, their relationship remains underexplored. Using Circ-Seq and mass spectrometry data, we perform a genome-wide analysis of mistranscriptions and mistranslations in five model organisms, and find that genes with frequent...

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