Article
Characterization of hepatitis B virus surface gene mutations from Huzhou, eastern China.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 4 May 2026
Han Zihan, Jin Fang, Luo Peng, Li Dongli, Zhong Jianfeng, Tong Zhaowei, Qian Fuchu
Abstract excerpt
BACKGROUND: Amino acid (AA) substitutions in the hepatitis B virus (HBV) S gene are key drivers of diagnostic evasion, vaccine breakthrough infections and immune escape. Understanding regional mutation profiles is essential for public health intervention. This study aimed to characterize the prevalence and mutation patterns of the HBV S gene in eastern China. METHODS: In this cross-sectional study, serum samples...
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