Article
Frequency of hepatitis B surface antigen variants (HBsAg) in hepatitis B virus genotype B and C infected East- and Southeast Asian patients: Detection by the Elecsys® HBsAg II assay.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2018
Kim Hyon Suk, Chen Xinyue, Xu Min, Yan Cunling, Liu Yali, Deng Haohui, Hoang Bui Huu, Thuy Pham Thi Thu, Wang Terry, Yan Yiwen, Zeng Zhen, Gencay Mikael, Westergaard Gaston, Pabinger Stephan, Kriegner Albert, Nauck Markus, Seffner Anja, Gohl Peter, Hübner Kirsten, Kaminski Wolfgang E
Abstract excerpt
BACKGROUND: To avoid false negative results, hepatitis B surface antigen (HBsAg) assays need to detect samples with mutations in the immunodominant 'a' determinant region, which vary by ethnographic region. OBJECTIVE: We evaluated the prevalence and type of HBsAg mutations in a hepatitis B virus (HBV)-infected East- and Southeast Asian population, and the diagnostic performance of the Elecsys® HBsAg II...
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