Article
Surface gene variants of hepatitis B Virus in Saudi Patients.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Jan 2000
Al-Qudari Ahmed Y, Amer Haitham M, Abdo Ayman A, Hussain Zahid, Al-Hamoudi Waleed, Alswat Khalid, Almajhdi Fahad N
Abstract excerpt
BACKGROUND/AIMS: Hepatitis B virus (HBV) continues to be one of the most important viral pathogens in humans. Surface (S) protein is the major HBV antigen that mediates virus attachment and entry and determines the virus subtype. Mutations in S gene, particularly in the "a" determinant, can influence virus detection by ELISA and may generate escape mutants. Since no records have documented the S gene mutations in...
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