Article
Hepatitis B virus genotypes and variants.
Cold Spring Harbor perspectives in medicine - 1 May 2015
Lin Chih-Lin, Kao Jia-Horng
Abstract excerpt
At least 10 hepatitis B virus (HBV) genotypes (A to J) with distinct geographic distributions and several HBV mutants, including precore/core promoter mutations and pre-S/S deletion mutations, have been recognized to be not only predictive of liver disease progression but also associated with response to antiviral therapy. HBV genotype-specific pathogenesis may contribute to heterogeneous clinical outcomes in...
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