Article
Evolutionary Analysis of Pre-S/S Mutations in HBeAg-Negative Chronic Hepatitis B With HBsAg < 100 IU/ml.
Frontiers in public health - 1 Jan 2021
Wu Yingping, Zhu Zhiqiang, Wu Jianyong, Bi Wenzi, Xu Wei, Xia Xiaoping, Han Dongsheng
Abstract excerpt
Background: Hepatitis B surface antigen (HBsAg) and viral load are important clinical indicators for antiviral therapy. Few studies have evaluated viral sequence biomarkers predicting the risk of hepatocellular carcinoma (HCC) in the stage, which show a low serological response (HBsAg < 100 IU/ml) and high viral levels (HBV DNA > 2,000 IU/ml). This study aims to determine the trend of the biological prevalence...
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