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Prevalence of S gene mutations within the major hydrophilic region of hepatitis B virus in patients in Dongguan, southern China.

Archives of virology - 1 Oct 2017

Li Siping, Xie Mingyu, Li Wenrui, Peng Qi, Zhong Baimao, Lu Xiaomei, Ma Qiang

Abstract excerpt

HBsAg point mutations within the major hydrophilic region (MHR) have frequently been reported to be associated with diagnostic failure, vaccine escape and immunotherapy escape. However, the prevalence of escape mutations in chronic hepatitis B (CHB) patients has not been systematically studied in patients from southern China within the past decade. This study aimed to determine the prevalence of escape mutations...

Topics

Adult
Biomarkers
China
DNA, Viral
Female
Genotype
Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Serologic Tests

Source

Identifiers

PMID: 28600703
DOI: 10.1007/s00705-017-3437-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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