Hepatitis B surface gene variants isolated from blood donors with overt and occult HBV infection in north eastern Egypt.

doi:10.1186/s12985-015-0389-y

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Article

Hepatitis B surface gene variants isolated from blood donors with overt and occult HBV infection in north eastern Egypt.

Virology journal - 30 Sept 2015

Kishk Rania, Nemr Nader, Elkady Abeer, Mandour Mohamed, Aboelmagd Mohamed, Ramsis Nevene, Hassan Mohamed, Soliman Nashaat, Iijima Sayuki, Murakami Shuko, Tanaka Yasuhito, Ragheb Mostafa

Abstract excerpt

BACKGROUND: Major hydrophilic region in genomic HBV extending from aa99 to aa169, clustered with a highly conformational epitope, is critical to the antigenicity of hepatitis B surface antigen (HBsAg) and may affect the diagnosis of HBV in HBV screening test. So, this study aimed to characterize variants of S gene product of hepatitis B virus (HBV) isolated from patients with overt or occult HBV infection in...

Topics

Adult
Amino Acid Substitution
Blood Donors
DNA, Viral
Egypt
Female
Genetic Variation
Genotype
Hepatitis B Antibodies
Hepatitis B Surface Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B virus

Humans

Male

Middle Aged

Molecular Sequence Data

Mutation, Missense

Sequence Analysis, DNA

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26420301
DOI: 10.1186/s12985-015-0389-y
PMCID: PMC4588243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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