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Article

Causal effect between systemic inflammatory cytokines and osteoporotic pathological fractures: A bidirectional Mendelian randomization study.

Medicine - 31 Oct 2025

Wang Heyuan, Wang Dan

Abstract excerpt

Osteoporosis is a prevalent metabolic bone disorder that significantly impairs patients' quality of life. Mounting evidence suggests a close relationship between systemic inflammation and bone metabolism, yet the causal nature of this association remains unclear. This study aims to elucidate potential causal links between circulating inflammatory factors and osteoporotic pathological fractures. We employed a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41261570
DOI: 10.1097/MD.0000000000044636
PMCID: PMC12582674

Genes

CXCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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