Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of circulating inflammatory proteins on osteoporosis and fractures: evidence from genetic correlation and Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Zheng Qingcong, Wang Du, Lin Rongjie, Li Zhechen, Chen Yuchao, Chen Rongsheng, Zheng Chunfu, Xu Weihong

Abstract excerpt

Objective: There is a controversy in studies of circulating inflammatory proteins (CIPs) in association with osteoporosis (OP) and fractures, and it is unclear if these two conditions are causally related. This study used MR analyses to investigate the causal associations between 91 CIPs and OP and 9 types of fractures. Methods: Genetic variants data for CIPs, OP, and fractures were obtained from the publicly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibroblast Growth Factor-23
Share to Fractures, Bone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Osteoporosis

Share to Osteoporotic Fractures

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 38757000
DOI: 10.3389/fendo.2024.1386556
PMCID: PMC11097655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of circulating inflammatory proteins on osteoporosis and fractures: evidence from genetic correlation and Mendelian randomization study.PMID 38757000Read ↗

Causal effect between systemic inflammatory cytokines and osteoporotic pathological fractures: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

The causal role of circulating inflammatory markers in osteoporosis: a bidirectional Mendelian randomized study.Semantic proximity Read ↗

Genetically predicted inflammatory cytokines and bone health outcomes: A 2-sample Mendelian randomization study.Semantic proximity Read ↗

A Mendelian Randomization Study of Cardiovascular Proteins, Immune Cell Traits, and Lifestyle Factors.Semantic proximity Read ↗

The effect of IL-1R1 and IL-1RN polymorphisms on osteoporosis predisposition in a Chinese Han population.Semantic proximity Read ↗

Causal relationship between circulating levels of cytokines and bone mineral density: A mendelian randomization study.Semantic proximity Read ↗

Causal relationship between Interleukin-27 expression levels and osteoporosis: a bidirectional mendelian randomization study.Semantic proximity Read ↗

Unveiling Epigenetic Molecular Mechanisms in Bone Fracture Risk: Insights From 731 Immune Cells, 1400 Metabolites, and Critical Genetic Pathways.Semantic proximity Read ↗

The Causal Effects Between Circulating Inflammatory Proteins and Osteoarthritis: A Mendelian Randomization and Transcriptomic AnalysisSemantic proximity Read ↗

Association between circulating inflammatory proteins and gout: A Mendelian randomization study.Semantic proximity Read ↗

Genetic insight into the putative causal proteins and druggable targets of osteoporosis: a large-scale proteome-wide mendelian randomization studySemantic proximity Read ↗

Causal associations of interleukins and osteoporosis: A genetic correlation study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.