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Article

Genetically predicted inflammatory cytokines and bone health outcomes: A 2-sample Mendelian randomization study.

Medicine - 6 Mar 2026

Zhong Yujia, Yang Fang, Chen Weiyin

Abstract excerpt

Circulating inflammatory factors have been implicated in various bone health outcomes, but the causal relationships remain unclear. We applied 2-sample Mendelian randomization to investigate the effects of 41 inflammatory factors on 5 bone health outcomes: osteoarthritis (OA), knee osteoarthritis (KOA), hip osteoarthritis, osteoporosis (OP), and rheumatoid arthritis (RA). We used publicly available summary...

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Identifiers

PMID: 41790639
DOI: 10.1097/MD.0000000000047939
PMCID: PMC12975193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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