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Causal Relationship Between Osteoporosis, Bone Mineral Density, and Osteonecrosis: A Bidirectional Two-Sample Mendelian Randomization Study

2024-10-28

Abstract excerpt

<title>Abstract</title> <p>Background Osteonecrosis (ON) is a debilitating orthopedic condition characterized by bone cell death due to impaired blood supply, leading to structural changes and disability. Osteoporosis (OP), a systemic skeletal disease, results in reduced bone density and quality, making bones fragile and prone to fractures. Although distinct, OP and ON share several risk factors such as corticos...

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Literature Corpus work
62563349-0c99-558d-aca2-9fe1f0b31d31
DOI
10.21203/rs.3.rs-4910241/v1
Open publication

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Causal Relationship Between Osteoporosis, Bone Mineral Density, and Osteonecrosis: A Bidirectional Two-Sample Mendelian Randomization StudyDOI 10.21203/rs.3.rs-4910241/v1
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