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Article

Unraveling the genetic basis of the causal association between inflammatory cytokines and osteonecrosis.

Frontiers in endocrinology - 1 Jan 2024

Lu Yining, Pei Yan, Gao YiMing, Zhao FeiFei, Wang Ling, Zhang Yingze

Abstract excerpt

Background: Previous studies have reported that the occurrence and development of osteonecrosis is closely associated with immune-inflammatory responses. Mendelian randomization was performed to further assess the causal correlation between 41 inflammatory cytokines and osteonecrosis. Methods: Two-sample Mendelian randomization utilized genetic variants for osteonecrosis from a large genome-wide association study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38745949
DOI: 10.3389/fendo.2024.1344917
PMCID: PMC11091469

Genes

IL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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