Article
Potential association of rheumatic diseases with bone mineral density and fractures: a bi-directional mendelian randomization study.
BMC musculoskeletal disorders - 5 Jul 2024
Hong Chen-Xuan, Pan Yan-Zheng, Dai Feng-Bo
Abstract excerpt
BACKGROUND: Previous studies have implicated rheumatoid arthritis as an independent risk factor for bone density loss. However, whether there is a causal relationship between rheumatic diseases and bone mineral density (BMD) and fractures is still controversial. We employed a bidirectional Mendelian analysis to explore the causal relationship between rheumatic diseases and BMD or fractures. METHODS: The rheumatic...
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