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Nitrofuran-Based STING Inhibitors

4 Sept 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide The cGAS-STING pathway plays a central role in the host response to foreign DNA. While cGAS-STING signaling is essential for antiviral immunity, aberrant STING activation is observed in amyotrophic lateral sclerosis (ALS), lupus, and autoinflammatory diseases such as Aicardi-Goutières syndrome (AGS) and STING associated vasculopathy with onset in infancy (SAVI)....

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PMID: 40978405
DOI: 10.1021/acsomega.5c05578

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