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Article

A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists.

Antiviral research - 1 Nov 2017

Liu Bowei, Tang Liudi, Zhang Xiaohui, Ma Julia, Sehgal Mohit, Cheng Junjun, Zhang Xuexiang, Zhou Yan, Du Yanming, Kulp John, Guo Ju-Tao, Chang Jinhong

Abstract excerpt

Stimulator of interferon genes (STING) is an endoplasmic reticulum transmembrane protein that serves as a molecular hub for activation of interferon and inflammatory cytokine response by multiple cellular DNA sensors. Not surprisingly, STING has been demonstrated to play an important role in host defense against microorganisms and pharmacologic activation of STING is considered as an attractive strategy to treat...

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Identifiers

PMID: 28982551
DOI: 10.1016/j.antiviral.2017.10.001
PMCID: PMC5789800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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