Article

Orthosteric STING inhibition elucidates molecular correction of SAVI STING

2024-06-18

Abstract excerpt

STING is broadly implicated in diseases ranging from cancer, autoimmune disease, neurodegeneration to rare, monogenic diseases. 1 Early drug discovery campaigns focused on STING activation as a promising platform for cancer immunotherapy yet failed in multiple clinical trials due to lack of efficacy thus far. 2 Current research and development activities concentrate on STING inhibition for treating autoimmune di...

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Literature Corpus work: 8ba10116-af42-55ef-8f4b-8b93e9438a32
DOI: 10.1101/2024.06.18.596881

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