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Article

Methods of Assessing STING Activation and Trafficking.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Pokatayev Vladislav, Yan Nan

Abstract excerpt

The signaling adapter protein STING is crucial for the host immune response to cytosolic DNA and cyclic dinucleotides. Under basal conditions, STING resides on the endoplasmic reticulum (ER ) , but upon activation, it traffics through secretory pathway to cytoplasmic vesicles, where STING activates downstream immune signaling. Classical STING activation and trafficking are triggered by binding of cyclic...

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Identifiers

PMID: 28808969
DOI: 10.1007/978-1-4939-7237-1_10
PMCID: PMC5715460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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