Genetic markers at the crossroads: toll-like receptor polymorphisms and Plasmodium vivax malaria parasitological aspects from the Brazil-French Guiana border.

doi:10.1093/trstmh/traf061

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Article

Genetic markers at the crossroads: toll-like receptor polymorphisms and Plasmodium vivax malaria parasitological aspects from the Brazil-French Guiana border.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 3 Nov 2025

Cerilo-Filho Marcelo, Ramirez Aína D R, Barbosa Vanessa S, Correa Renata B, de Jesus Myrela C S, Sampaio Marrara P, Miceli Leonardo A, Reis Nathália F, Menezes Rubens A O, Gomes Margarete S M, Pimenta Tamirys S, Cassiano Gustavo C, Silva José R S, Storti-Melo Luciane M, Baptista Andrea R S, Machado Ricardo L D

Abstract excerpt

BACKGROUND: Studies relating allelic variants in toll-like receptor (TLR) genes to the parasitological profile of Plasmodium vivax malaria are scarce. Therefore, we sought to assess whether polymorphisms in these genes can influence the clinical and parasitological aspects of individuals with P. vivax malaria in an endemic area from the Brazil-French Guiana border. METHODS: We analyzed 76 patients with P. vivax...

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PMID: 40578841
DOI: 10.1093/trstmh/traf061

Genes

TLR4
TLR6
TLR9

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