Article
Polymorphisms in TLRs influence circulating cytokines production in Plasmodium vivax malaria: TLR polymorphisms influence cytokine productions in malaria-vivax.
Cytokine - 1 Oct 2018
Costa Allyson Guimarães, Ramasawmy Rajendranath, Val Fernando Fonseca Almeida, Ibiapina Hiochelson Najibe Santos, Oliveira Amanda Carvalho, Tarragô Andréa Monteiro, Garcia Nadja Pinto, Heckmann Maria Izabel Ovellar, Monteiro Wuelton Marcelo, Malheiro Adriana, Lacerda Marcus Vinícius Guimarães
Abstract excerpt
The efficiency of the immune system has been shaped throughout the evolutionary process allowing adaptations. In a Plasmodium vivax infection, the host attempts to develop an innate immune response to keep in check the parasite that is associated with inflammatory and regulatory processes. Production of pro-inflammatory and regulatory cytokines simultaneously appears to be a balancing mechanism for the host to...
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