Article
Influence of trem-1 gene polymorphisms on cytokine levels during malaria by Plasmodium vivax in a frontier area of the Brazilian Amazon.
Cytokine - 1 Sept 2023
de Jesus Myrela C S, Cerilo-Filho Marcelo, Ramirez Aina D R, Menezes Rubens A O, Gomes Margarete S M, Cassiano Gustavo C, Gurgel Ricardo Q, Silva José R S, Moura Tatiana R, Pratt-Riccio Lilian R, Baptista Andrea R S, Storti-Melo Luciane M, Machado Ricardo L D
Abstract excerpt
BACKGROUND: The immunopathology during malaria depends on the level of inflammatory response generated. In this scenario, the TREM-1 has been associated with the severity of infectious diseases and could play an important role in the inflammatory course of malaria. We aimed to describe the allelic and genotypic frequency of four polymorphisms in the trem-1 gene in Plasmodium vivax-infected patients and to verify...
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