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Article

Tests for dominant-lethal effects of 1,2-dibromo-3-chloropropane (DBCP) in male and female mice.

Mutation research - 1 Jan 2000

Generoso W M, Cain K T, Hughes L A

Abstract excerpt

DBCP was studied for dominant-lethal effects in male and female mice and for total reproductive effects in females. In males it was administered either intraperitoneally or subcutaneously while in females it was given only by the former route. No DBCP-related response was observed in either males or females indicating its ineffectiveness in inducing chromosomal aberrations or cytotoxicity in mouse germ cells....

Topics

Animals
Dose-Response Relationship, Drug
Female
Genes, Dominant
Genes, Lethal
Male
Mice
Mutagenicity Tests
Mutation
Propane
Reproduction
Sex Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 4000172
DOI: 10.1016/0165-1218(85)90012-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-4000172-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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