Article
Bleomycin: female-specific dominant lethal effects in mice.
Mutation research - 1 Dec 1992
Sudman P D, Rutledge J C, Bishop J B, Generoso W M
Abstract excerpt
Limited comparative data in mice indicate that chemical mutagens that induce dominant lethal mutations in males are not necessarily effective in females, but those which are effective in females are generally equally or more effective in males. Recently, however, a few chemicals have been identif...
Topics
- Animals
- Bleomycin
- Chromosome Aberrations
- Female
- Genes, Dominant
- Genes, Lethal
- Litter Size
- Male
- Mice
- Mutagenicity Tests
- Mutation
- Oocytes
- Oogenesis
- Spermatogenesis
- Zygote