Dominant lethal test with rats exposed to 1,3-dichloropropene by inhalation.

doi:10.1002/(sici)1098-2280(1998)32:4<351::aid-em9>3.0.co;2-m

Back to search

Article

Dominant lethal test with rats exposed to 1,3-dichloropropene by inhalation.

Environmental and molecular mutagenesis - 1 Jan 1998

Gollapudi B B, Cieszlak F S, Day S J, Carney E W

Abstract excerpt

The potential of 1,3-dichloropropene (1,3-DCP) to induce dominant lethal mutations in the germ cells of male CD rats following inhalation exposure was investigated. Groups of 11-week-old males (30 animals/group) were exposed to 1,3-DCP vapors by inhalation at targeted concentrations of 0 (negativ...

Topics

Allyl Compounds
Animals
Embryo Implantation
Female
Fertility
Genes, Lethal
Hydrocarbons, Chlorinated
Inhalation Exposure
Insecticides
Male
Mutagens
Mutation
Pregnancy Rate
Rats
Rats, Sprague-Dawley
Spermatogenesis

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.