Article
Dominant lethal test with rats exposed to 1,3-dichloropropene by inhalation.
Environmental and molecular mutagenesis - 1 Jan 1998
Gollapudi B B, Cieszlak F S, Day S J, Carney E W
Abstract excerpt
The potential of 1,3-dichloropropene (1,3-DCP) to induce dominant lethal mutations in the germ cells of male CD rats following inhalation exposure was investigated. Groups of 11-week-old males (30 animals/group) were exposed to 1,3-DCP vapors by inhalation at targeted concentrations of 0 (negative control), 10, 60, and 150 ppm for 10 weeks (6 hr/day, 7 days/week). An additional group of 30 males (designated the...
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