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Targeted deaminase‐free T‐to‐G and C‐to‐K base editing in rice by fused human uracil DNA glycosylase variants

16 Jan 2025

Abstract excerpt

Base editors (BEs), a groundbreaking class of genome editing tools, enable precise single-nucleotide alterations at target genomic sites, leading to mutations that either disable or enhance gene functions, thus significantly advancing plant functional genomics research and crop enhancement (Li et al., 2023). In plants, significant advancements have been made in DNA base editors that can directly modify adenine...

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PMID: 39817669
DOI: 10.1111/pbi.14583

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