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High-efficiency plastome base editing in rice with TAL cytosine deaminase

12 Jul 2021

Abstract excerpt

Genome editing has been widely applied in nuclei but not so in organelles such as the mitochondria and chloroplasts. The challenge for organelle genome editing is the limited accessibility of editing reagents to the compartments of organelles (Zhu et al., 2020). Recently, fusion proteins of cytidine deaminase domain (DddAtox) and transcription activator-like effectors (TALEs) have been developed for DNA base...

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PMID: 34265443
DOI: 10.1016/j.molp.2021.07.007

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