Article
Targeted G-to-T base editing for generation of novel herbicide-resistance gene alleles in rice.
Journal of integrative plant biology - 1 Jun 2024
Tian Yifu, Li Xinbo, Xie Jiyong, Zheng Zai, Shen Rundong, Cao Xuesong, Wang Mugui, Dong Chao, Zhu Jian-Kang
Abstract excerpt
A newly developed rice guanine base editor (OsGTBE) achieves targeted and efficient G-to-T editing (C-to-A in the opposite strand) in rice. Using OsGTBE to edit endogenous herbicide-resistant loci generated several novel alleles conferring herbicide resistance, highlighting its utility in creating valuable germplasm and enhancing genetic diversity..
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