Causal relationship between hypertension and ischemic stroke: A two-sample Mendelian randomization study

Abstract excerpt

BACKGROUND: Ischemic stroke (IS) is a well-recognized risk factor for human health and has become a major cause of the global burden of disease over the past decades. Determining the correlation between hypertension and IS is important for the prevention of IS. In epidemiologic studies, researches have reported a strong association between hypertension and IS. However, there is a great deal of heterogeneity...

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