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Genetically Determined Blood Pressure, Antihypertensive Drugs, and Genes with Clinical Outcome after Ischemic Stroke: Evidence from Mendelian Randomization

2023-04-10

Abstract excerpt

<h4>Background</h4> Observational studies suggest a robust association between blood pressure (BP) and functional outcomes in ischemic stroke patients. We sought to identify novel associations of the genetic basis of 3-month functional outcome after ischemic stroke based on a Mendelian randomization (MR) framework. <h4>Methods</h4> We selected genetic variants associated with systolic and diastolic BP and BP-lower...

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Literature Corpus work
6ab200d7-8dfb-58f2-aee1-fe866b67356e
DOI
10.1101/2023.04.09.23288342
Open publication

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Genetically Determined Blood Pressure, Antihypertensive Drugs, and Genes with Clinical Outcome after Ischemic Stroke: Evidence from Mendelian RandomizationDOI 10.1101/2023.04.09.23288342
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