Article
Hypertensive disorders of pregnancy and stroke: a univariate and multivariate Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Qu Kang, Li Mingxi, Yu Peng, Jiang Wei, Dong Ming
Abstract excerpt
Background: Hypertensive disorders of pregnancy (HDP) are associated with an increased risk of stroke later in life in multiparous women. However, causality of these associations remains unclear. This study employed 2-sample univariate and multivariate Mendelian randomization (MR) to assess the causal connection between HDP and stroke. Methods: Genetic variants for HDP and two subtypes were identified from recent...
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