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Article

Effect of the Blood Pressure and Antihypertensive Drugs on Cerebral Small Vessel Disease: A Mendelian Randomization Study.

Stroke - 1 Jul 2024

Ma Yazhou, Wang Mengmeng, Chen Xin, Yao Jianrong, Ding Yiping, Gao Qianqian, Zhou Jiayi, Lian Xuegan

Abstract excerpt

BACKGROUND: Previous studies yielded conflicting results about the influence of blood pressure (BP) and antihypertensive treatment on cerebral small vessel disease. Here, we conducted a Mendelian randomization study to investigate the effect of BP and antihypertensive drugs on cerebral small vessel disease. METHODS: We extracted single-nucleotide polymorphisms for systolic BP and diastolic BP from a genome-wide...

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Identifiers

PMID: 38818733
DOI: 10.1161/STROKEAHA.123.045664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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