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Mendelian Randomization in Stroke: A Powerful Approach to Causal Inference and Drug Target Validation

12 Aug 2021

Abstract excerpt

Stroke is a leading cause of death and disability worldwide. However, our understanding of its underlying biology and the number of available treatment options remain limited. Mendelian randomization (MR) offers a powerful approach to identify novel biological pathways and therapeutic targets for this disease. Around ~100 MR studies have been conducted so far to explore, confirm, and quantify causal relationships...

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PMID: 34456968
DOI: 10.3389/fgene.2021.683082

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