Article
Causal effects of gestational hypertension on women's health: A Mendelian randomization analysis.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Aug 2026
Luo Haizhao, Mei Wen, Ye Jingwen, Liu Lei, Liang Weiqiang, Shu Yi
Abstract excerpt
OBJECTIVE: Gestational hypertension (GH) is linked to complications impacting women's health, with confounded causal links in observational studies. This study used Mendelian randomization (MR) to investigate GH's effects on women's diseases. METHODS: To reduce confounding and identify robust GH associations, we selected 149 single-nucleotide polymorphisms (SNPs) as instrumental variables (IVs). The data were...
Topics
- Humans
- Female
- Mendelian Randomization Analysis
- Hypertension, Pregnancy-Induced
- Pregnancy
- Polymorphism, Single Nucleotide
- Genome-Wide Association Study
- Women's Health
- Stroke
- Risk Factors