Article

Causal effect of Insulin Resistance on Small Vessel Stroke and Alzheimer's Disease: A Mendelian Randomization Analysis

2021-02-25

Abstract excerpt

<title>Abstract</title> <p>Background The causal effect of insulin resistance on small vessel stroke and Alzheimer Disease was controversial in previous studies. Methods We selected 12 single-nucleotide polymorphisms (SNPs) associated with body mass index (BMI)-adjusted fasting insulin levels and 5 SNPs associated with gold standard measures of insulin resistance as instrumental variables in Mendelian randomiza...

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Literature Corpus work: 5cd07575-f511-5b0a-a5d1-a231b61d2328
DOI: 10.21203/rs.3.rs-267358/v1

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