Article
Positive genetic effect of hypertension family history on stroke: A cross Mendelian randomization study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Oct 2024
Chi Xilyu, Zhang Jingruo, Yin Xiaohu
Abstract excerpt
BACKGROUND: Clinical observational study demonstrated that hypertension is an independent risk factor for stroke. Furthermore, both hypertension and stroke exhibit genetic predispositions. However, the genetic relationship between hypertension and stroke in first-degree relatives remains unclear. METHOD: The Genetic effects were validated using an across-Mendelian randomization (MR) approach. The Genome-Wide...
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