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TtAgo-coupled-multiplex-digtal-RPA-CRISPR/Cas12a (TCMDC) for EGFR mutations detection.

Talanta - 1 Feb 2025

Zhuang Jianjian, Jiang Hong, Lou Jiang, Zhang Yu

Abstract excerpt

Epidermal Growth Factor Receptor (EGFR) is an important target for the early evaluation, treatment, and postoperative follow-up in non-small cell lung cancer (NSCLC). Current detection technologies suffer from extended detection time and high rate of false positive amplification. Therefore, the development of rapid, highly sensitive and specific detection methods is of great significance for improving the...

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PMID: 39522277
DOI: 10.1016/j.talanta.2024.127162

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