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Sensitive and specific colorimetric DNA detection by invasive reaction coupled with nicking endonuclease-assisted nanoparticles amplification.

Biosensors & bioelectronics - 15 Apr 2015

Zou Bingjie, Cao Xiaomei, Wu Haiping, Song Qinxin, Wang Jianping, Kajiyama Tomoharu, Kambara Hideki, Zhou Guohua

Abstract excerpt

Colorimetric DNA detection is preferable to methods in clinical molecular diagnostics, because no expensive equipment is required. Although many gold nanoparticle-based colorimetric DNA detection strategies have been developed to analyze DNA sequences of interest, few of them can detect somatic mutations due to their insufficient specificity. In this study, we proposed a colorimetric DNA detection method by...

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PMID: 25460881
DOI: 10.1016/j.bios.2014.10.077

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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