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Article

Sanger Sequencing Reveals Novel Variants in GLO-1, ACE, and CBR1 Genes in Patients of Early and Severe Diabetic Nephropathy.

Medicina (Kaunas, Lithuania) - 20 Sept 2024

Shah Syed Zubair Hussain, Rashid Amir, Majeed Asifa, Ghafoor Tariq, Azam Nadeem

Abstract excerpt

Background and Objectives: Diabetes is a global health issue, with approximately 50% of patients developing diabetic nephropathy (DN) and 25% experiencing early and severe forms of the disease. The genetic factors contributing to rapid disease progression in a subset of these patients are unclear. This study investigates genetic variations in the GLO-1, CBR-1, and ACE genes associated with early and severe DN....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lactoylglutathione Lyase

Share to Mutation, Missense

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 39336582
DOI: 10.3390/medicina60091540
PMCID: PMC11433688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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