SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.

doi:10.1007/s00125-014-3459-6

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SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.

Diabetologia - 1 Mar 2015

Germain Marine, Pezzolesi Marcus G, Sandholm Niina, McKnight Amy J, Susztak Katalin, Lajer Maria, Forsblom Carol, Marre Michel, Parving Hans-Henrik, Rossing Peter, Toppila Iiro, Skupien Jan, Roussel Ronan, Ko Yi-An, Ledo Nora, Folkersen Lasse, Civelek Mete, Maxwell Alexander P, Tregouet David-Alexandre, Groop Per-Henrik, Tarnow Lise, Hadjadj Samy

Abstract excerpt

AIMS/HYPOTHESIS: The genetic determinants of diabetic nephropathy remain poorly understood. We aimed to identify novel susceptibility genes for diabetic nephropathy. METHODS: We performed a genome-wide association study using 1000 Genomes-based imputation to compare type 1 diabetic nephropathy cases with proteinuria and with or without renal failure with control patients who have had diabetes for more than 15...

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PMID: 25476525
DOI: 10.1007/s00125-014-3459-6
PMCID: PMC5438751

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SORBS1

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