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Article

Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes.

JAMA - 25 Aug 2010

Ma Ronald C W, Tam Claudia H T, Wang Ying, Luk Andrea O, Hu Cheng, Yang Xilin, Lam Vincent, Chan Alfred W H, Ho Janice S K, Chow Chun-Chung, Tong Peter C Y, Jia Weiping, Ng Maggie C Y, So Wing-Yee, Chan Juliana C N

Abstract excerpt

CONTEXT: Protein kinase C-beta (PKC-beta) is a cell-signaling intermediate implicated in development of diabetic complications. OBJECTIVE: To examine the risk association of PKC-beta 1 gene (PRKCB1) polymorphisms and end-stage renal disease (ESRD) in an 8-year prospective cohort of Chinese patien...

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Identifiers

PMID: 20736472
DOI: 10.1001/jama.2010.1191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20736472-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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