Article
The genetic polymorphisms and activity of glyoxalase 1 as a risk factor for acute coronary syndrome in South Indians with type 2 diabetes mellitus.
Gene - 15 Nov 2023
Bora Sushmita, Adole Prashant Shankarrao, Vinod Kolar Vishwanath, Pillai Ajith Ananthakrishna, Ahmed Shaheer
Abstract excerpt
OBJECTIVE: The individuals' genetic traits predispose them to a higher or lower risk of Type 2 diabetes mellitus (T2DM) and its complications, for example, acute coronary syndrome (ACS). As carbonyl stress is responsible for the pathogenesis and complications of T2DM, and glyoxalase 1 (GLO1) is the most crucial determinant of carbonyl stress, the study aimed to explore the association between GLO1 gene...
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