Glucokinase Regulatory Protein Gene Polymorphism as a Predictive Biomarker for Early Renal Injury in Newly Diagnosed Early-Onset Type 2 Diabetes Mellitus.

doi:10.1002/dmrr.70197

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Glucokinase Regulatory Protein Gene Polymorphism as a Predictive Biomarker for Early Renal Injury in Newly Diagnosed Early-Onset Type 2 Diabetes Mellitus.

Diabetes/metabolism research and reviews - 1 Jul 2026

Zhang Rui, Zhang Ping, Ba Tianhao, Zhao Yilin, Liu Wei, Zhang Simin, Zou Xiantong, Luo Yingying, Deng Wei, Wang Qiuping, Qi Lin, Li Yufeng, Wang Wenbo, Zhong Liyong, Huo Lili, Li Chunxia, Hao Dejun, Zhang Yajing, Xu Yan, Wang Fang, Han Xueyao, Ren Qian, Ji Linong

Abstract excerpt

AIMS: Glucokinase regulatory protein gene (GCKR) polymorphisms have been linked to progressive renal dysfunction in diabetic populations. However, their role in early renal injury of diabetic kidney disease (DKD) remains unclear. This study aimed to investigate the association between GCKR genetic variants and early renal impairment in newly diagnosed early-onset type 2 diabetes mellitus (T2DM). METHODS: A total...

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PMID: 42339691
DOI: 10.1002/dmrr.70197

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GCKR

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Glucokinase Regulatory Protein Gene Polymorphism as a Predictive Biomarker for Early Renal Injury in Newly Diagnosed Early-Onset Type 2 Diabetes Mellitus.PMID 42339691Read ↗

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